The Mercure Centro Port Macquarie is conveniently located between Sydney and Brisbane. The hotel is near the city center, making it within walking distance to many shopping centers and restaurants. The beach is a short drive away and recreational activities are within ten minutes' walk from the hotel. The rainforest is an hour or so away. The airport is less than a thirty minute drive from the Mercure Centro Port Macquarie. Hotel staff can make travel arrangements by request.

There are 71 standard rooms and deluxe suites at the Mercure Centro Port Macquarie. Each room in the hotel has a high speed Internet connection, air conditioning, private bathroom, satellite TV, DDD telephone, safe and a private balcony or terrace. Room and laundry service are available for a fee.

This hotel was built in 2007 and has a four and a half star rating. The Mercure Centro Port Macquarie has a bar, a spa, a swimming pool and a gym. A conference center has state of the art AV equipment and can hold up to medium sized events. An onsite restaurant serves seafood and international dishes.